Can nitrobenzene be reduced by NaBH4?

NaBH4, a mild reducing agent, does not reduce nitroaromatic compounds under normal conditions. However, several NaBH4 catalytic systems have been developed for the reduction of nitroaromatic compounds.

Can sodium borohydride reduce nitro group?

SODIUM BOROHYDRIDE Reduces aldehydes and ketones to corresponding alcohols. Sodium borohydride is not reactive to esters, epoxides, lactones, carboxylic acids, nitro compounds and nitriles, but reduces acyl chlorides.

Can NaBH4 reduce Nitro to Amine?

NaBH4 in the presence of catalytic amounts of Ni(OAc)2. 4H2O reduces varieties of nitro compounds to their corresponding amines.

What is the reduction of nitrobenzene?

It is generally accepted that the reduction of nitrobenzene to aniline consists of two main steps: first, nitrobenzene is reduced to phenylhydroxylamine (PHA) through a 4-electron exchange, with nitrosobenzene (NSB) as an intermediate. Then, a 2-electron reduction step converts PHA to aniline (Scheme 1) [16,17].

Can nitrobenzene be reduced by LiAlH4?

The structure of the compound formed, when nitrobenzene is reduced by lithium aluminium hydride (LiAlH4) is= Hint :Lithium aluminum hydride is a strong reducing agent for polar double bonds. Since the nitro group contains polar double bonds, Lithium aluminum hydride reduces aromatic nitro compounds to azo products.

Does LiAlH4 reduce double bond?

LiAlH4 is a strong, unselective reducing agent for polar double bonds, most easily thought of as a source of H-. It will reduce aldehydes, ketones, esters, carboxylic acid chlorides, carboxylic acids and even carboxylate salts to alcohols.

Why is an excess of sodium borohydride used?

NaBH4 is a very effective and selective reducing agent. This is the main reason why a slight excess of sodium borohydride is used customarily in reduction reactions. NaBH4 is above all used for reducing aldehydes and ketones. Aldehydes can be reduced selectively in the presence of ke- tones.

How do you reduce nitro groups?

One of the most important reactions of aromatic substituents is the reduction of nitro groups to amines. This can be done using two general methods: Addition of an easily oxidized metal like iron (Fe), tin (Sn) or zinc (Zn) in the presence of acid, such as HCl (but often just written, “H+ “) will convert NO2 to NH2.

What happens when nitrobenzene is reduced with LiAlH4?

The structure of the compound formed, when nitrobenzene is reduced by lithium aluminium hydride (LiAlH4) is= Since the nitro group contains polar double bonds, Lithium aluminum hydride reduces aromatic nitro compounds to azo products.

What products are obtained by reduction of nitrobenzene under different conditions?

Complete answer: When nitro compounds are reduced, then amines are formed. The bulky nitrobenzene is reduced using zinc, and sodium hydroxide. The reduction of $N{{O}_{2}}$is in such a way that it gets converted to amines, the amines are attached with themselves and then benzene rings are attached.

How is sodium borohydride used to reduce nitrobenzene?

Metal sulfides and sodium borohydride were used in the reduction of nitrobenzene. Catalysts caused a ten-fold increase in the conversion of nitrobenzene to aniline.

How are metal sulfides used to reduce nitrobenzene?

Metal sulfides and sodium borohydride were used in the reduction of nitrobenzene. Catalysts caused a ten-fold increase in the conversion of nitrobenzene to aniline. The new system was successfully used in the reduction of several nitro aromatics.

How is the reaction of nitrobenzene and NABH 4 performed?

In a typical procedure, nitrobenzene (1 equiv) dissolved in ethanol was treated with NaBH 4 (3 equiv) in the presence of the corresponding catalyst (10 mol %). The reactions were carried out in a closed scintillation vial and sonicated for 60 min. The reaction was also performed without catalyst for comparison.

What is the isolated yield of nitrobenzene derivatives?

As seen in Table 4, the newly developed system was employed successfully in the reduction of nitrobenzene derivatives in moderate (58%) to high (>90%) isolated yields. The isolated yield was independent of the nature of the substituents.