How do you treat Purpura Hemorrhagica?
Treatment. A veterinarian usually starts the horse on dexamethasone, a corticosteroid, which eases the immune reaction. In addition, antibiotics will stop any other respiratory infections and prevent further infections. The disease is often mild and the horse recovers well.
What causes purpura Hemorrhagica in horses?
Purpura hemorrhagica is an immune mediated condition caused by vasculitis, or an inflammation of the blood vessels. This causes bleeding and swelling and is believed to be an allergic reaction to a previous infection of any streptococcal bacteria, such as strangles, or a virus.
What causes purpura Hemorrhagica in humans?
Purpura occurs when small blood vessels burst, causing blood to pool under the skin. This can create purple spots on the skin that range in size from small dots to large patches. Purpura spots are generally benign, but may indicate a more serious medical condition, such as a blood clotting disorder.
What type of hypersensitivity is Purpura Hemorrhagica?
equi M protein (SeM); purpura hemorrhagica is classified as a type III hypersensitivity reaction and is caused by immune complexes (antigen and immunoglobulins) that deposit on the walls of small blood vessels (resulting in vasculitis) or renal glomerular capillaries and vessels (resulting in glomerulonephritis).
What are the signs and symptoms of purpura?
Symptoms of purpura
- Low platelet count, which may lead to increased bleeding after an injury, bleeding gums or nose, or blood in urine or bowel movements.
- Sore, swollen joints, particularly in the ankles and knees.
- Gut problems such as nausea, vomiting, diarrhea, or stomach pain.
What is HSP virus?
HSP is an autoimmune disease that is often triggered by an upper respiratory infection. Symptoms include a rash caused by bleeding under the skin, arthritis, belly pain, and kidney disease. Most children recover fully. But some children may have kidney problems.
What are the universal presenting signs of immune thrombocytopenic purpura?
- Easy or excessive bruising.
- Superficial bleeding into the skin that appears as pinpoint-sized reddish-purple spots (petechiae) that look like a rash, usually on the lower legs.
- Bleeding from the gums or nose.
- Blood in urine or stools.
- Unusually heavy menstrual flow.
Does HSP ever go away?
Most of the time, HSP improves and goes away completely within a month. Sometimes HSP relapses; this is more common when a child’s kidneys are involved. If HSP does come back, it is usually less severe than the first time.
What does palpable purpura look like?
A variety of rashes, the most classic of which is “palpable purpura” –purplish–red spots, usually found on the legs. These spots can usually be felt by the examiner’s fingertips, hence the descriptor “palpable”. This is a classic example of palpable purpura.