Is artesunate amodiaquine?
ARTESUNATE AMODIAQUINE WINTHROP is indicated for the treatment of uncomplicated cases of malaria due to Plasmodium falciparum strains which are susceptible to amodiaquine as well as to artesunate.
How is artesunate amodiaquine taken?
Artesunate/amodiaquine, sold under the trade name Camoquin among others, is a medication used for the treatment of malaria. It is a fixed-dose combination of artesunate and amodiaquine. Specifically it recommended for acute uncomplicated Plasmodium falciparum malaria. It is taken by mouth.
What are the side effects of artesunate amodiaquine?
Common side effects of Artesunate include: Loss of appetite on days 1-2. Dizziness on days 1-2. Nausea on days 1-2….Additional Side Effects of Artesunate can include:
- Hives.
- Rash.
- Hemoglobinuria.
- Seizures.
- Neuropsychiatric reactions.
- Reversible neurologic changes.
What does amodiaquine treat?
Amodiaquine has been widely used to treat malaria. Fatal adverse reactions have been reported in adults taking it for prophylaxis. This has led some authorities to suggest it is withdrawn as a first line treatment for malaria.
How long does amodiaquine stay in the body?
The pharmacokinetic properties of each drug are relatively well characterized: lumefantrine and its metabolite desbutyl-lumefantrine have terminal elimination half-lives of 1–10 days [1, 13,14,15,16], while desethylamodiaquine, the active metabolite of amodiaquine, has a half-life of 4–10 days [1, 17,18,19,20,21,22].
What is the best malaria drug in Ghana?
In Ghana, artesunate–amodiaquine (AA) is the first choice, with artemether–lumefantrine (AL) and dihydroartemisinin-piperaquine (DHAP) as alternatives. The use of the ACT coupled with the implementation of other interventional measures has resulted in significant reduction in the incidence of malaria in Ghana lately.
Is amodiaquine same as chloroquine?
Amodiaquine is being used in India for presumptive treatment as an alternative to chloroquine in areas with chloroquine resistant P. falciparum. Keeping in view the toxicity of amodiaquine, studies have been undertaken to evaluate the advantage of the drug over chloroquine in the treatment of P. falciparum malaria.
What is the difference between artemether and artesunate?
Artesunate is the water soluble sodium hemisuccinyl ester, whilst artemether is the lipid soluble methyl ether of dihydroartemisinin. Both artesunate and artemether are metabolized in vivo to the highly active antimalarial metabolite, dihydroartemisinin (DHA) [5, 6].
What is ACT treatment for malaria?
Artemisinin-based combination therapies (ACTs) are the best anti-malarial drugs available now. Artemisinin enhances efficacy and has the potential of lowering the rate at which resistance emerges and spreads.
What brand is quinine?
Drug Name : Quinine. Quinine(Qualaquin) generic is an antimalarial agent, prescribed for malaria and nighttime leg muscle cramps. It works by killing the malaria parasite.
Which injection is the best for malaria?
Injection of artesunate is recommended by the World Health Organization (WHO) for treating adults and children that have severe malaria as studies have shown that it results in fewer deaths compared to quinine treatment.
Which injection is good for malaria?
The standard treatment for severe malaria is an intravenous infusion of quinine or quinidine [1,2]. Quinine may also be administered as an intramuscular injection. A loading dose of 20 mg/kg is recommended to reduce the time needed to reach effective concentrations in the blood [3].