Is inverted papilloma serious?

The majority of inverted papillomas are not cancerous. In some 5-15 percent of cases, inverted papillomas can harbor a common form of skin cancer called squamous cell carcinoma. Although inverted papillomas will not metastasize to other areas of the body, they do have a tendency to be locally aggressive.

What causes inverted papilloma in sinus?

Inverted papilloma is a benign epithelial growth in the underlying stroma of the nasal cavity and paranasal sinuses. The pathogenesis of this lesion remains unclear although allergy, chronic sinusitis and viral infections have been suggested as possible causes.

Is inverted papilloma cancer?

Inverted papillomas are noncancerous tumors that form in the posterior aspect of the nasal cavities. As they grow, they can sometimes extend into the paranasal sinuses or orbits. Occasionally, inverted papillomas can undergo a malignant transformation into an aggressive form of cancer called squamous cell carcinoma.

How do you get rid of nasal papillomas?


  1. Complete surgical excision: treatment of choice for benign papilloma in good surgical candidates (because of high rates of recurrence if incompletely excised)
  2. Radiation: considered only in inoperable disease with malignant transformation or in poor surgical candidates.

Can you see inverted papilloma?

An ENT or sinus surgeon can look into your nose with a small telescope. Because inverted papilloma have characteristic appearance, often the diagnosis may made through appearance alone.

Do nasal papillomas hurt?

These warts do not often hurt but can be unsightly. HPV is not cancer, but the HPV virus can cause changes in the body that may lead to cancer.

Are nasal papillomas common?

Although one-third of these tumors arise in the head and neck, their occurrence in the nasal cavity is rare, representing only 4% of all head and neck schwannomas.

What does inverted papilloma look like?

Most inverted papillomas can be found during a physical examination of the nasal and sinus cavities. They have a reddish-grey appearance and may bleed when touched. The septum may be bowed by the mass of the inverted papilloma.

Is a papilloma a tumor?

Papillomas are tumors that arise from body tissues that cover all body surfaces, from the skin to internal organs (epithelial tissue). These tumors form finger-like branches that extend outward. Papillomas on the skin are called warts and verrucae.

How fast do inverted papillomas grow?

The time from first histological diagnosis of IP to invasive carcinoma was only 3 months which is short compared with literature. In their review, Mirza et al2 calculated a mean duration to develop into a carcinoma of 52 months (range 6 to 180 months).

Why is it called inverted papilloma?

The term ‘inverted papilloma’ is derived from the histological appearance. The neoplastic epithelium inverts into the underlying stroma and the lesion is endophytic rather than exophytic from a microscopic viewpoint [6].

Where are inverted papillomas found in the nose?

Inverted papillomas are benign tumors found in either the mucous that lines the nose or the paranasal sinuses, the four air-filled spaces that surround the nasal cavity under, above, and between the eyes.

What are the characteristics of an inverted papilloma tumor?

Inverted papilloma is a rare sinonasal tumor that mainly occurs in adults during the 5th decade. Three characteristics make this tumor very different from other sinonasal tumors: a relatively strong potential for local destruction, high rate of recurrence, and a risk of carcinomatous evolution.

What kind of surgery is needed for sinonasal inverted papilloma?

Inverted papilloma is a benign sinonasal tumor, the precise etiology of which is unknown. High risk of recurrence and the risk of carcinomatous progression warrant wide surgical resection, ideally based on the tumor insertion point as found on radiologic examination.

How are inverted papillomas diagnosed at Mount Sinai?

Rhinologists at Mount Sinai use the latest technologies to diagnose inverted papillomas, including: Nasal endoscopy – When patients come in for an evaluation, our physicians look for tumors using an endoscope—a narrow tube with a small, flexible camera that passes easily through the nose and sinuses.