What is the normal range of DCP?
Results: The mean DCP value was 17.5 mAU/mL in the normal subjects, and the detection limit was 10 mAU/mL for this revised DCP kit. The positivity rate for DCP in patients with HCC was 60% by the revised DCP kit, in contrast to 40% by the conventional DCP kit.
What is PIVKA test?
Protein induced by vitamin K absence-II (PIVKA-II) is a potential screening marker for hepatocellular carcinoma (HCC). Limited data are available about its utility in discriminating neoplastic from regenerative nodules at ultrasonography (US) evaluation in cirrhotic patients.
What is DCP protein?
Des-gamma-carboxy prothrombin (DCP), also known as the protein induced by vitamin K absence or antagonist II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin.
What does pivka stand for?
Protein induced by vitamin K absence-II (PIVKA-II) – also known as des-γ-carboxy-prothrombin-has been. identified as a serum biomarker linked to HCC.
What is DCP lab test?
Des-gamma-carboxy prothrombin (DCP) is an abnormal form of prothrombin, a clotting factor produced by the liver. This test measures the amount of DCP in the blood to help evaluate whether treatment for one type of liver cancer, hepatocellular carcinoma (HCC), is effective.
What is pivka II assay?
Elecsys® PIVKA-II is an immunoassay for the quantitative measurement of protein induced by vitamin K absence or antagonist-II (PIVKA‑II) in human serum and plasma. The assay is used as an aid in the diagnosis of hepatocellular carcinoma (HCC).
How do you calculate DCP in nutrition?
To find out the digestible crude protein (DCP) content of a feed,multiply the digestibilty coefficient of the crude protein with the crude protein content of the feedstuff.
What is TDN and DCP?
– TDN (Total Digestible Nutrients) is a measure of the amount of energy that can be obtained from a unit quantity of the feed. – DCP (Digestible Crude Protein) is a measure of the amount of protein in the feed that can be digested and absorbed by the animal.
What is a DCP blood test for?
What is DCP blood test for?
How does Des gamma carboxy prothrombin ( DCP ) test work?
Des-gamma-carboxy prothrombin (DCP) Des-gamma-carboxy prothrombin (DCP) is an abnormal form of prothrombin, a clotting factor produced by the liver. This test measures the amount of DCP in the blood to help evaluate whether treatment for one type of liver cancer, hepatocellular carcinoma (HCC), is effective. DCP can be produced by liver tumors,…
How is prothrombin converted to gamma carboxyglutauta acid?
In normal liver, prothrombin undergoes post-translational carboxylation before release into the peripheral blood. The carboxylation converts specific amino-terminal glutamic acid residues to gamma-carboxyglutamic acid.
What makes DCP a nonfunctional form of prothrombin?
DCP is a nonfunctional prothrombin resulting from a lack of carboxylation of 10 glutamic acid residues in the N-terminal portion of the molecule. In normal liver, prothrombin undergoes post-translational carboxylation before release into the peripheral blood.
How is DCP used as a biomarker for HCC?
Therefore, this noncarboxylated form (DCP) has been used as an HCC biomarker. DCP is considered a complementary biomarker to alpha fetoprotein (AFP) and third electrophoretic form of lentil lectin-reactive AFP% (AFP-L3%) for assessing the risk of developing HCC.