Why are C57BL 6 mice used?
C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss. They are also susceptible to diet-induced obesity, type 2 diabetes, and atherosclerosis. Macrophages from this strain are resistant to the effects of anthrax lethal toxin.
What species is C57BL 6?
C57BL/6, often referred to as “C57 black 6”, “C57” or “black 6”, is a common inbred strain of laboratory mouse. It is the most widely used “genetic background” for genetically modified mice for use as models of human disease.
How big is a 6 week old mouse?
JAX Mice Strain – C57BL/6J
| Age (Weeks) | Body Weight (grams; mean± st. dev) | |
|---|---|---|
| 4 | 14.7 ± 1.8 | 16.5 ± 2.6 |
| 5 | 17.8 ± 1.1 | 20.7 ± 1.8 |
| 6 | 18.5 ± 0.9 | 21.9 ± 1.8 |
| 7 | 19.0 ± 1.0 | 23.6 ± 1.5 |
Are C57Bl 6 mice genetically identical?
C57BL/6 mice are the most used inbred strain in research. Our C57BL/6 mouse colonies are genetically identical within each strain, making them free of genetic differences that could impact research results.
What is DB db mice?
db/db Mice (JAX™ Mice Strain) Details db/db mice are used to model phase 1 to 3 of diabetes type II and obesity. Mice that are homozygous for the diabetes spontaneous mutation (Leprdb) demonstrate morbid obesity, chronic hyperglycemia, pancreatic beta cell atrophy and come to be hypoinsulinemic.
How much does a C57BL 6 cost?
Specialized Inventory
| Age in Weeks | Quantity |
|---|---|
| 1-999 | |
| 3 to 4 | $48.00 |
| 5 to 6 | $60.00 |
| 7 to 8 | $70.00 |
What is C3H?
C3H/HeJ mice, commonly called C3H, are used as a general purpose strain in a wide variety of research areas including cancer, infectious disease, sensorineural, and cardiovascular biology research.
What do you do if you find baby mice?
Call a wildlife rehabilitator. If you find a baby wild mouse (or an empty nest of baby mice), call your local wildlife rehabilitation office. Transferring the baby mouse to a wildlife professional is the best chance it has for survival.
When can baby mice survive on their own?
Baby mice subsist on their mother’s milk for about a month before they are strong enough to leave the nest. More than that, the mother mouse also teaches them how to urinate. The pups are unlikely to survive unless they are at least 3 weeks old when they become orphaned.
Which is the best strain of black 6 mice?
Attempts to enhance the replicability and to reduce the variability in basic research has led to the recommendation to use isogenic mice. The C57BL/6 strain has evolved as a gold standard strain for this purpose. However, C57BL/6 mice are maintained as substrains by multiple vendors.
What are the characteristics of a C57BL / 6 mouse?
Appearance and behavior. C57BL/6 mice have a dark brown, nearly black coat. They are more sensitive to noise and odours and are more likely to bite than the more docile laboratory strains such as BALB/c. They are good breeders.
Which is the most common genetic background for mice?
C57BL/6, often referred to as “C57 black 6”, “C57” or “black 6”, is a common inbred strain of laboratory mouse . It is the most widely used “genetic background” for genetically modified mice for use as models of human disease. They are the most widely used and best-selling mouse strain, due to the availability of congenic strains,…
How old are C57BL / 6J male and female mice?
Study-ready aged C57BL/6J males and females are available off-the-shelf between 25 – 90 weeks of age. Aged C57BL/6J mice have research applications that include immunology, cancer, longevity interventions, and biomarker studies.