What does low ABS CD8 CD57 Lymphs mean?
What does it mean if your CD8-CD57 + Lymphs (Absolute) result is too low? The number of CD57 cells is decreased in chronic Lyme disease patients, particularly those with pronounced neurologic symptoms.
What is normal CD57 level in Lyme?
CD57 is typically 60 -360 cells/μl and although the CD57 count rebounds back to the normal range, Striker and Winger have shown that 51% of patients with Lyme disease have significantly lower levels of CD57 prior to antibiotic treatment [123] .
What does CD57 positive mean?
The CD57 is expressed on both natural killer (NK) cells and T lymphocytes. The CD57 test measures CD57 positive NK cells only. The test is performed on EDTA whole blood. In patients with low CD 57 counts, Lyme disease and Chlamydophila pneumoniae infections should be included in differential diagnosis.
What is CD57 a marker for?
CD57 is a very useful marker of NK cell maturation, identifying cells with potent cytotoxic potential but decreased sensitivity to cytokines and reduced replicative potential.
What does a low CD57 mean?
Test interpretation: Low CD-57 occurs in chronic Lyme or when the disease has been active for over 1 year. The count reflects the degree of infection. It is not a diagnostic test but is used as a marker for Lyme being active.
Is Lyme disease a chronic condition?
Chronic Lyme disease occurs when a person who’s treated with antibiotic therapy for the disease continues to experience symptoms. The condition is also referred to as post Lyme disease syndrome or post-treatment Lyme disease syndrome.
What is Lyme disease CDC?
Lyme disease is caused by the bacterium Borrelia burgdorferi and rarely, Borrelia mayonii. It is transmitted to humans through the bite of infected blacklegged ticks. Typical symptoms include fever, headache, fatigue, and a characteristic skin rash called erythema migrans.
Is Borrelia burgdorferi a virus?
Borrelia burgdorferi sensu stricto is a bacterial species of the spirochete class in the genus Borrelia, and is one of the causative agents of Lyme disease in humans.
What else causes low CD57?
Low CD57 counts are usually associated with a systemic infection, but the type of infection need not be of a specific type. Usually cell wall deficient bacteria can trigger this, but there are many, many types of cell wall deficient bacteria that cause systemic infections.
What does CD8 count mean?
The CD8 cells are T cells with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and bind to the infected cell and kill it. A normal CD8 cell count is about 300.
What is CD57 test?
The CD57 Test is used by some physicians to discretionarily confirm suspicions of chronic Lyme disease and remission. The test is not an official or 100% accurate means of diagnosing chronic Lyme or determining stage of infection.
What is ABS lymph?
abs is absolute count and lym is lymphocytes which is one of the five white blood cells. the absolute lymphocyte norm is 1.3-4.5. if a number is higher than the norms then it could be from a virus, or leukemia. the white blood cells are more when they have something bad to fight off. Loading…